describe

An indispensable tool for liquid sample scanning electron microscopy (SEM) observation!

The benefits of achieving high-resolution imaging and compositional analysis of particles in their original state in liquids are:

1. Overcoming the problem of particle agglomeration in traditional drying processes and accurately reflecting the state of particles in the liquid;
2. The use of high vacuum mode to analyze liquid samples sealed in the sample holder overcomes the problem of contamination of electron microscope components caused by direct analysis of water containing samples (ESEM mode or Low Vacuum mode);
3. By sealing magnetic materials, contamination of electron microscope components can be avoided.

Product principle

Ultra-thin window

Made using semiconductor technology, the surface can be treated to have hydrophilicity, hydrophobicity, or a combination of both, to meet different application needs; When analyzing, the observed sample automatically adheres to the ultra-thin window, thus obtaining the best image resolution.

Liquid sample pool

Integrated with microfluidics, high-precision probes, and leak proof design, the liquid sample pool can control and monitor the microenvironment status. Obtain the optimal microfluidic transport model through computational fluid dynamics simulation optimization. Adopting special mechanical design to improve usage efficiency, sample installation can be completed within 1 minute.

Product performance

1. Good applicability.

Suitable for various models of scanning electron microscopes from brands such as FEI, JEOL, Hitachi, ZEISS, TESCAN, Phenom, etc. It can also be used for in-situ observation of light/fluorescence microscopes.

2. Easy to use

Using special mechanical design, the sample installation can be completed within 1 minute.

3. Flexible customization is possible

Samples can be placed on wafers or biochips for in-situ observation.

4. High resolution

The maximum magnification can reach 200000 times, allowing for clear observation of particles as small as 10nm.

• • • • • • First to apply electron beam testing to raw fluids and liquid samples.
          • Detect and monitor spray materials in their original state (especially liquid).

Comparison of in-situ observation and observation after drying of liquid samples

application area

1. Energy

Silver paste	Aluminum paste	Copper paste

2. Semiconductor and Electronics Industry

Chemical mechanical polishing solution Particle size and composition analysis in polishing solution; Particle aggregation and dispersion analysis to solve the problem of process defect monitoring.	Metal electroplating The precipitation of heavy metal particles in the deteriorating electroplating solution during the PCB process leads to abnormalities in the end product, therefore immediate monitoring and analysis are required.
Paint and coatings Analyze the particle distribution and dispersion in paint and coating suspensions.	Welding paste, thermal grease, encapsulated silver paste Liquid process analysis to ensure that there are no abnormalities in the production process of related paste and silver paste products

Using analysis software to automatically obtain particle size and distribution information in images

Component analysis: can distinguish particles with different components such as Ag and Cu in the same image

3. Biology and pharmaceuticals

Analysis of nanomedicine size, dispersibility, and concentration; Surface morphology analysis

Improve the production process of polystyrene

Defective polystyrene production process	Liposomes Size/distribution/concentration

4Biology and pharmaceuticals—–Cell morphology

Appearance and morphology of adherent/suspended cells and fungi; Microbial/cellular tissue observation

Pheromone	blackberry
Fungal (Tremella) spores	probiotics